Enzymatic Dissolution of Actinic Keratosis Scales
Actinic keratosis is one of the most common sun-induced pre-cancerous skin lesions and precursor of squamous cell carcinoma as well as basal cell carcinoma cancer. If treated early, almost all actinic keratosis can be eliminated without becoming skin cancers.
Actinic keratosis is a scaly or crusty bump that arises on the skin surface. The base may be light or dark, tan, pink, red, or a combination of these, or the same color as your skin. The scale or crust is horny, dry, and rough, and is often recognized by touch rather than sight. Occasionally it itches or produces a pricking or tender sensation. It can also become inflammed and surrounded by redness. In rare instances, actinic keratoses can even bleed.
The skin abnormality or lesion develops slowly and generally reaches a size from an eighth to a quarter of an inch. Early on, it may disappear only to reappear later. You will often see several actinic keratosis at a time. An actinic keratosis is most likely to appear on the face, ears, scalp, neck, backs of the hands and forearms, shoulders, and lips - the parts of the body most often exposed to sunshine. The growths may be flat and pink or raised and rough.
Individuals with light skin are most likely to develop actinic keratosis. The condition is directly associated to sun exposure, and therefore is sometimes called "solar keratosis". In fact, fair-skinned individuals living in sunny climates have over 50 percent chance of developing actinic keratosis. Individuals aged 40 and up are at high risk, with more men affected by this common, pre-cancerous condition than women. Furthermore, regardless of age, all individuals with blue eyes and or childhood freckling are at a higher risk for actinic keratosis.
Usually, lesions develop as a single, small plaque on the face of people aged 20-30 years with light coloring and significant sun exposure; they gradually progress in sun-exposed areas, such as the nose, the forehead, and the cheeks.
During periods of depressed immunity, the visible and the subclinical lesions flare and become inflammatory red and scaly. This depression of the immune system can occur following intense ultraviolet light exposure or with systemic chemotherapy for other carcinomas.
Over the years, the lesions gradually progress, and approximately 1 in 20 lesions eventually turns into invasive carcinomas. These lesions are typically the more red and inflammed, elevated, and indurated lesions. In very hyperkeratotic lesions, the invasive component of the carcinoma is at the base of the lesion and is often not seen until a physician removes the overlying plaque.
The morphology of atypical cells in both actinic keratosis and squamous cell carcinoma is identical. The risk of progression to squamous cell carcinoma (the most common form of skin cancer) is minimal. But up to 60% of squamous cell carcinoma cases begin as actinic keratosis. Regression of actinic keratosis occurs when sun exposure is decreased and mild lesions are healed.
Actinic Keratosis Treatment Options
Treatment is often indicated to prevent the cells from invading the dermis and possibly metastasizing. If a lesion exhibits evidence of possible dermal invasion, such as marked erythema (redness of the skin caused by dilatation and congestion of the capillaries, often a sign of inflammation or infection) ulceration, tenderness, bleeding, and especially induration (hardening of a normally soft tissue), a physician will consider performing a biopsy.
The best therapy is one that addresses minor actinic keratosis scaly formations early, and here is where BIOSKINTREATMENT plays a significant role.
Grinds down mild actinic keratosis through enzyme dissolution of keratin and abnormal tissues and prevents the growth of new actinic keratosis scaly formations
Acts like an exfoliant by eliminating dead cells and scaly lesions before they grow.
Also destroys pathogens, heals and regenerates damaged tissue.
It nourishes your skin and protects it from free radicals.
Improves the skin's elasticity, and leaves it silky soft and soothed.
BIOSKINTREATMENT is a non prescription, natural skin care remedy, with absolutely no side effects.
The cream is made with a natural biological ingredient, collected from live land snails, the same they use to quickly repair their own skin and shell when damaged. It is contained in the mucin secreted by the snails, (we gather it through a process that is safe for them). It is a viscose liquid that is made into an odorless white cream with no alien, synthetic chemicals. Analysis of the mucin has determined that it contains activators of skin growth factors and antimicrobial peptides. Also presents natural anti-inflammatory and immune modulating proteins, glycoproteins, glycosaminoglycans (a group of polysaccharides with high molecular weight that contain amino sugars and often form complexes with proteins. Also called mucopolysaccharide) and copper.
The results are:
- A healthier appearance of the skin
- A thicker skin
- Normal skin color,
- Normal skin texture and
- A hydrated skin
Depending on the treatment method used, people may remain free of Actinic Keratosis for months and possibly years. However, individuals with significant photodamage and those who fail to minimize sun exposure are at increased risk for the development of additional Actinic Keratosis, as well as skin cancer.
Preventing Actinic Keratosis
Apply a broad spectrum sunscreen (protects against both UVA and UVB rays) that has a Sun Protection Factor (SPF) of 15 or more, every day.
Avoid deliberate tanning. Even when wearing sunscreen, sunbathing is not safe. Tanning beds and sunlamps are not safe alternatives because they too emit UV rays.
Stay out of the sun between 10 a.m. and 4 p.m. This is when the sun’s rays are the strongest. Seek shade whenever possible. If you don’t see your shadow or your shadow is shorter than you, it is important to seek cover.
Wear protecting clothing when you are on the sun.
A wide-brimmed hat is a must to protect your face and neck from the harmful rays. Wear sunglasses that provide 100% UV protection.
BIOSKINTREATMENT will not heal severe keratosis that may have already a cancerous formation.
Actinic Keratosis Profilaxis
Gentle home exfoliation by the action of enzymes to reduce actinic keratosis
BIOSKINTREATMENT brings you the ONLY skin renewal product that incorporates natural skin renewal activators and biological enzymes that gently dissolve or "digest" mild and moderate actinic keratosis formations and damaged or worn out cells while at the same time triggers the proliferation of fibroblasts that give rise to new connective tissues and hydrating molecules within the skin: new collagen and elastin cells and glycosaminoglycans and proteoglycans. The result is a coordinated biological regulation of the skin renewal process and thus healthy skin and advanced skin rejuvenation.
The beauty and genius of nature's most complete and balanced biological skin revival serum is that it works by creating an equivalent of a NON TRAUMA exfoliation which means that your skin will react to the messanger molecules and the enzymes that recognize and degrade damaged cells and non functional tissues by activating its own biological response modifiers thereby supporting your body's immune system and repair mechanisms to treat skin injuries (cuts, bruises, abrasions, acne lesions, scars, wounds, burns), dysfunctional tissues (keratosis, keloid and hypertrophic scars, excess dryness) and prevent over reactions that further destroy tissues and immune-mediated inflammatory skin disorders (inflammatory acne, rosacea, eczema and most dermatitis reactions).
And it will do so in an environment that has also been provided with all the molecule messengers that are necessary for a) the recognition of those cells and tissues that are damaged and need to be "digested" by the enzymes and b) an orchestrated regeneration or biosynthesis of new healthy tissues and with antioxidants that limit damage from free radical generation from the cells that participate in the immune system and create them to fight invading microbes.
When the enzymes "digest" or dissolve the topmost micron of skin (part of the outer layer that is no thicker than a sheet of paper, slowly and over a period of time) unlike all other such methods as glycolic acid peels, dermabrasion or laser resurfacing, there is no heat and blistering, so there is nothing to heal.
When you burn your skin, your body creates healing protein like collagen and elastin bands, pus, melanin, water, and antibodies (inflamm-aging) that rush to the aid of the trauma. In that case, there actually IS a burn to tend to...
However, during your BIOSKINTREATMENT™ treatment, there is NOT any burn or trauma repair. The proteins that transport the repair elements to the epidermis and underlying stratum corneum are flooded with your own molecules and DNA. The new skin growth that is waiting to be exposed is not only smoother and tighter on its own, but it has just been soaked with those reparative proteins and water holding molecules that hydrated your skin and flooded to the surface to come to the aid of the 'NON TRAUMA EXFOLIATION'.
For actinic keratosis scales and for hard, rough and old scars clinical trials have shown that the best results from chemical, physical exfoliation or laser treatments is achieved when the treatment is combined with SKIN REGENERATING ACTIVATORS. The reason is after the skin has been damaged by exfoliators it is IMPERATIVE that skin healing progresses at a quick pace.
Skin healing is a highly ordered systemic process that involves the coordinated regulation of cell proliferation and migration, and tissue remodeling .
Skin Exfoliation usually only involves removal of dead skin cells. BIOSKINTREATMENT™ is unlike any other exfoliation treatment available today because BIOSKINTREATMENT™ is the only system that gently exfoliates with ENZYMES & NATURAL SKIN RENEWAL ACTIVATORS that signal your system to get rid of damaged skin cells and target the cells that play the biggest role in keeping skin young, the fibroblasts, which are deep down in the mesoderm (middle layer) and stimulate them to reproduce all the structural components of healthy skin. And the whole process is coordinated at the pace needed to restore a healthy and beautiful skin naturally.
The Skin Renewal Activators are natural skin regenerating peptides and glycomolecules that signal your body to accelerate skin renewal . The same molecules are found in healthy human skin when it is wounded. They coordinate and regulate cell proliferation and migration and tissue remodeling. But as we age these regulatory growth factors slow down their activity and it is necessary to supply them topically to achieve the same skin renewal achieved by youngsters.
Reaching the fibroblasts
The point is enzymes help the peptides and glyco messengers to reach the fibroblasts. Skin is not fragile but admirably tough, more a barrier than a membrane. That's why the outer (and toughest) layer, the stratum corneum, is also called the horny layer. It's about ten microns thick -a lot in the dermatology world- and consists of layers of the same dead cells (corneocytes) that compose fingernails. The horny layer is often compared to a brick-and-mortar construction: The large cells of the epidermis are packed tightly together, while the small spaces between them are filled with fats (lipids). The design is foolproof: The corneocytes keep foreign material out, and the lipids make sure water stays in. The second layer (the epidermis) is about 80µm micrometres or microns thick. The third layer (the dermis) contains the capillaries and nerve endings and is several millimeters thick.
A micrometre is one-millionth of a metre - one-thousandth of a millimetre. One micron is about a tenth of the diameter of a droplet of mist or fog. It can be written in scientific notation as 1×10−6 m, meaning 1 / 1,000,000 m.
Yet it's on this hard ground that most products are meant to work. Most skin-care products focus on moisturizing the 'dead' layer of the skin, the 10 microns or so that require water so they don't feel dry, but that is not enough and in most cases it is deleterious for it ends wetting the skin too much.
The combination of tough stratum corneum layer and live epidermis makes it extremely difficult for external substances to penetrate skin. Traditionally, only small water-soluble molecules are able to diffuse slowly into the skin. Physical exfoliation of 10 or so microns, specially of rough scar tissues helps active ingredients to penetrate more easily the outer layer of the skin into the epidermis and the basal layer, while they also polish the surface and make it softer and look and feel more even. If scars are new and damage to skin is minor, or for routine exfoliation the action of the enzymes in BIOSKINTREATMENT is best.
Gently Renew Your Skin by Enzyme Exfoliation with BIOSKINTREATMENT
BIOSKINTREATMENT LOTION clears skin of keratin bumps and regenerates healthy skin
The product is made with the same base as BIOSKINCARE plus Salix Nigra (Willow) Extract and Amorphophallus Konjac Root Powder for a more potent keratolytic effect that cleans the excess horny material of the skin by degrading keratin plugs and dissolving debris, damaged, abnormal and necrotic tissues. It decongests the skin as the enzymes in the snail serum and the natural salicylic acid in willow bark extract help to 'digest' all damaged structures into their amino-acid and other components, which also favors the regeneration of all the structural components of healthy skin.
It leaves your skin smooth, refreshed, soft and with use over a period of time it takes away keratosis pilaris, actinic keratosis scales, controls acne and reduces and even vanishes all types of skin blemishes: razor nicks and burns, roughness, blisters, scrapes, cuts, and the list can go on and on...
Made in the USA. 60 grams = 2 oz
One Bottle: $60
Ultra exfoliate rough scars and dull skin with BIOSKINEXFOL
Home microdermabrasion cream. Contains the same natural ingredients in BIOSKINTREATMENT but infused with micro-crystals so that you may rub it with your finger tips to remove old, hard, and tough scars or stretch marks by a physical breakdown of the scar tissues. Best also for oily skin and aged skin, actinic keratosis scales and pitted acne scars. Not for keloids and not if your skin is still fragile (use BIOSKINTREATMENT for a few months first to strengthen your skin). The compounded action of the physical abrasion and the enzymes in the cream liquefy damaged proteins more thoroughly helping to release amino-acids to aid in rebuilding damaged tissues quickly. Results are not only immediate, but compound over time and do not trigger inflamm-aging of delicate skin tissues.
Made in the USA. Two to Three Month's supply 120 grams = 4.23 oz
120 Gram Bottle: $89
Get rid of hiperpigmentation of scar areas and tissues and sun & age spots while reviving and protecting the skin from the effects of free radicals with BIO SKIN REJUVENATION
A deeply moisturizing natural skin care cream that replenishes the lipid barrier of the skin and triggers the repair of cells damaged by UV radiation and Free Radicals. Also gets rid of brown, sun and age spots, actinic keratosis scales and all types of skin blemishes. The same ingredients in BIOSKINTREATMENT with an added natural substance that reduces melanin hyperpigmentation and a biomimetic peptide that inhibits the accumulation of melanin pigments.
One Month's Supply 1.76 oz., 50 Gram Bottle: $79
Biological Skin Treatment Ingredient
Our products contain a biological serum created by a living creature. It is packed with enzymes, coenzymes, glycoproteins, glycosaminoglycans (hyaluronic acid), proteoglycans, peptides and oligoelements that (a) dissolve keratin plugs that obstruct the hair follicles and cause hyperkeratosis or acne, and dissolves damaged dysfunctional skin tissues by a process of enzyme exfoliation when applied at least twice a day on the affected skin areas for a while, (b) regenerate healthy skin by promoting the proliferation of fibroblasts and supporting microcirculation in capillaries, (c) scavenge oxygen radicals and the damaging effects of excessive solar radiation and (c) keep microbes in check by the action of antimicrobial peptides secreted on the skin and within the hair follicles.
It keeps the skin moisturized, prevents skin infection, repairs wounds, promotes scarless healing, and renews the skin.
The collection of the biological ingredient in our products is done by using a humanely method that inflicts no damage upon the little creatures from which we gather the biological compound that can not possible be replicated in even the most sophisticated laboratory.
Skin Treatment Products
Clears keratosis pilaris and actinic keratosis scales by the action of two ingredients: the enzymes in a biological serum and salicylic acid as is naturally in willow bark extract. As the keratin and damaged cells are broken down into their amino-acid and other components they are used for the regeneration of all the structural components of healthy skin. Product is in a 2oz pump bottle. Price is $60.
A home microdermabrasion cream with micro-crystals that breakdown hard, rough and old scar tissues, and allow for a deeper penetration of our natural skin moisturizing and regeneration complex contained in the microdermarasion cream.120 gram (4 oz) jar = $89.-
Medical care for actinic keratosis
As lesions progress, they can be treated with topical 5-fluorouracil. This medication is applied twice daily for a period of 3-4 weeks for facial lesions. Other body sites require longer treatment, with the arms needing 6-8 weeks. Treating the entire area of involvement is best.
During the treatment phase, the lesions become increasingly red, and small subclinical lesions become visible. This treatment can be temporarily disfiguring, with inflammatory and red ulcerations and crust formation. However, if the patient completes the treatment, the lesions usually heal within 2 weeks of stopping treatment, the complexion is smooth, and the actinic keratosis are improved.
Topical 5-fluorouracil treatment can be repeated on several occasions. The few residual lesions that are not completely cleared with 5-fluorouracil can then be treated surgically.
Photodynamic therapy (PDT) can also be used to treat multiple actinic keratoses. In this treatment, topical 5-aminolevulinic acid accumulates preferentially in the dysplastic cells. On exposure to irradiation with light of an appropriate wavelength, oxygen free radicals are generated and cell death results. Patients experience pain in the areas treated, which is similar in quantity to the pain resulting from topical 5-fluorouracil. One treatment with PDT appears to be as effective as 5-fluorouracil and may be considered in patients with contact sensitivity to 5-fluorouracil.
Surgical Care for Actinic Keratosis
Early lesions of actinic keratoses can be treated with destruction. Cryotherapy with liquid nitrogen is the most effective and practical method for treating actinic keratoses when a limited number of lesions are present. Liquid nitrogen, applied by swab or spray, is used for several seconds. As the cryotherapy wound heals, the actinic keratosis is sloughed off. These patients may need periodic re-treatment for small recurrences or for new lesions. Often, semiannual or annual monitoring and treatment are warranted.
Physical destruction using electrodesiccation (destruction of lesions or sealing off of blood vessels by monopolar high-frequency electric current) and curettage (scrapping of tissues with an instrument shaped like a scoop or spoon) is particularly effective when a person has hyperkeratotic lesions (scaly or hardenned keratin proteins on the surface of the skin).
Chemical peels may be used in patients with a number of facial lesions.
Dermabrasion may be used.
Adverse reactions such as scarring, textural changes, infection, and pigmentation alteration rarely occur.
If a lesion does not respond to treatment, obtaining a biopsy of the lesion should be considered to be certain that the lesion is not an invasive squamous cell carcinoma.
Cryosurgery may result in wounds, require time for wound healing, and may yield hypopigmentation (white spots) or scarring and although those side effects were acceptable in the past, many people now developing actinic keratosis have little tolerance for any time for wound healing or any cosmetic changes.